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Coronavirus Study finds Cannabis compounds can block COVID-19

Coronavirus Cannabis Study

Coronavirus Study finds Cannabis

US researchers have found that cannabis compounds have the ability to  prevent the virus that causes COVID-19 from entering human cells.  According to a study published last week by researchers from Oregon  State University.  

A Research article entitled “Cannabinoids Block Cellular Entry of  SARS-CoV-2 and the Emerging Variants” was published online by  the Journal of Natural Products.  

The study was led by Dr. Richard van Breemen, a researcher at Oregon  State University’s Global Hemp Innovation Center, who collaborated  with scientists at the Oregon Health & Science University.  

Cannabinoids are naturally occurring compounds found in the Cannabis  sativa plant. Of over 480 different compounds present in the plant, only  around 66 are termed cannabinoids. 

The most well-known among these compounds are the delta-9- tetrahydrocannabinol (∆9-THC), which is the main psychoactive  ingredient in cannabis. Cannabidiol (CBD) is another important  component, which makes up about 40% of the plant resin extract.

CBD oil

Researchers found that a pair of Cannabinoid compounds bind to the  SARS-CoV-2 spike protein, blocking the cellular entry of SARS-CoV-2.  Laboratory tests showed Cannabigerolic acid and Cannabidiolic acid were effective against the SARS-CoV-2 alpha variant B.1.1.7 and the beta variant B.1.351. These cannabinoid acid compounds are abundant in hemp and many hemp extracts,” Van Breemen said.  

“They are not controlled substances like THC, the psychoactive  ingredient in marijuana, and have a good safety profile in humans. And  our research showed the hemp compounds were equally effective against  variants of SARS-CoV-2, including variant B.1.1.7 (Alpha), which was  first detected in the UK, and variant B.1.351 (Beta), first detected in  South Africa.”

cannabis bud
“We thought we’d go about trying to find natural products that can stop  the virus from infecting cells or inhibit their ability to replicate and go  on to infect other individuals. We decided to attack the virus at the  starting point, where it enters the cell. That’s the same point at which  antibodies attack the virus,” Breemen said in an interview. The study stated that CBDA and CBGA are useful against some  variants of Covid. However, they have not been tested against the Delta  and Omicron variants of the coronavirus. This research shows how essential Cannabinoid compounds are and have medicinal value. This is an excellent thing for the cannabis cultivators also. Rich cannabinoid percentages in the cannabis plant have a more excellent economic value. MyfloraDNA offers a Cannabinoid Dominant testing service, a fast and accurate DNA  approach that enables you to determine which of your plants contain the genes associated with high or low THC or CBD production.
Reference :
  1. Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants  
Richard B. van Breemen, Ruth N. Muchiri, Timothy A. Bates, Jules B. Weinstein, Hans  C. Leier, Scotland Farley, and Fikadu G. Tafesse Journal of Natural Products Article  ASAP DOI: 10.1021/acs.jnatprod.1c00946 More Info
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